General Cell Based Assays
Meso Scale Discovery U-PLEX Human A2M ASY
The Meso Scale Discovery U-PLEX Human A2M Assay is a multiplex immunoassay kit for measuring Alpha-2-Macroglobulin (A2M) in human serum plasma and cell culture supernatant This electrochemiluminescent assay uses MSD s SECTOR Imager offering high sensitivity a broad dynamic range and low sample volume The kit includes a 96-well plate with capture antibodies detection antibodies and necessary calibrators and controls It enables rapid reproducible quantification of A2M crucial for regulating protease activity
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-GSK3α (Ser21) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-GSK3α (Ser21) Detection Kit, 10,000 Assay Points
Eurofins Discoverx PathHunter eXpress HRH2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0208E2CP0M)
The PathHunter HRH2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. histamine) based activation of HRH2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HRH2 and EA-tagged β-Arrestin-2. Activation of HRH2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter™ Human CXCL11 (CXCR3) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human CXCL11 (CXCR3) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CXCR3 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR75 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR75 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR75 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human IL-6 (IL6RA/IL6ST) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-6 (IL6RA/IL6ST) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL6RA/IL6ST. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR103 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR103 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR103 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Sigma Aldrich Fine Chemicals Biosciences Mitochondrial Membrane Pot
Mitochondria generate a potential across their membranes due to the activities of enzymes of the electron transport chain. During apoptosis collapse of the mitochondrial membrane potential (MMP) coincides with the opening of the mitochondrial permeability transition pores leading to the release of cytochrome c into the cytosol which in turn triggers other downstream events in the apoptotic cascade.
Eurofins Discoverx PathHunter eXpress OPRL1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0264E2CP0M)
The PathHunter OPRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. orphanin FQ) based activation of OPRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRL1 and EA-tagged β-Arrestin-2. Activation of OPRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Medchemexpress LLC cGAS Human His-SUM 5ug
The cGAS protein is a nucleotidyl transferase that crucially mediates innate immunity by catalyzing the formation of 2 3 -cGAMP from ATP and GTP upon binding to double-stranded DNA (dsDNA) As a DNA sensor cGAS detects exogenous and endogenous DNA triggering STING1 activation and type I interferon production cGAS Protein Human (His-SUMO) is the recombinant human-derived cGAS protein expressed by E coli with N-6 His N-SUMO labeled tag
Cayman Chemical LIpIdLaunchLNPMC3 Uptake K 1ea
Cayman’s LipidLaunch™ LNP-MC3 Uptake Kit (Green Fluorescence) is intended to serve as a starting point for laboratories to explore the uptake of LNPs by their target cell type without the need for specialized equipment. Optimal preparation conditions for the encapsulation of nucleic acids with LNPs must be determined by the end user.
Eurofins Discoverx PathHunter Human IL-17A (IL17RA/IL17RC) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-17A (IL17RA/IL17RC) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL17RA/IL17RC. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc HTRF Total IR-β (Insulin Receptor Beta) Detection Kit, Control Lysate
HTRF Total IR-β (Insulin Receptor Beta) Detection Kit, Control Lysate
Eurofins Discoverx PathHunter Human OPRM1 (Opioid mu) Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human OPRM1 (Opioid mu) Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure OPRM1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.